667.4K XNAS Volume
XNAS 19 Mar, 2025 1:23 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.85 per share. | 11 Feb 2025 | 140,182 | 625,948 | - | 3.9 | 539,701 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 3.70 per share. | 11 Feb 2025 | 75,324 | 883,089 | - | 3.7 | 278,699 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2025 | 332,465 | 958,413 | - | 0 | Common Stock | |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 28 Jan 2025 | 33,688 | 287,920 | - | 4.6 | 155,975 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 4.42 per share. | 28 Jan 2025 | 20,791 | 406,270 | - | 4.4 | 91,896 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2025 | 139,141 | 427,061 | - | 0 | Common Stock | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2025 | 176,400 | 693,268 | - | 0 | Common Stock | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 28 Jan 2025 | 3,220 | 516,868 | - | 4.6 | 14,909 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 4.42 per share. | 28 Jan 2025 | 30,823 | 616,038 | - | 4.4 | 136,238 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 4.55 per share. | 28 Jan 2025 | 46,407 | 646,861 | - | 4.6 | 211,152 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2025 | 139,141 | 402,331 | - | 0 | Common Stock | |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.55 per share. | 28 Jan 2025 | 2,109 | 400,222 | - | 4.6 | 9,596 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 28 Jan 2025 | 2,283 | 263,190 | - | 4.6 | 10,570 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 28 Jan 2025 | 33,753 | 265,473 | - | 4.6 | 156,276 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.42 per share. | 28 Jan 2025 | 20,791 | 379,431 | - | 4.4 | 91,896 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.42 per share. | 28 Jan 2025 | 17,250 | 402,431 | - | 4.4 | 76,245 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.63 per share. | 28 Jan 2025 | 1,673 | 307,081 | - | 4.6 | 7,746 | Common Stock |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 28 Jan 2025 | 139,141 | 446,222 | - | 0 | Common Stock | |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.55 per share. | 28 Jan 2025 | 26,541 | 419,681 | - | 4.6 | 120,762 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.78 per share. | 21 Jan 2025 | 125,000 | 199,548 | - | 4.8 | 597,500 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.52 per share. | 21 Jan 2025 | 125,000 | 449,548 | - | 4.5 | 565,000 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 4.80 per share. | 21 Jan 2025 | 125,000 | 324,548 | - | 4.8 | 600,000 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 275,000 | 275,000 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 400,000 | 400,000 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 1,105,000 | 1,105,000 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 275,000 | 275,000 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 Jan 2025 | 275,000 | 275,000 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.15 per share. | 02 Jan 2025 | 32,156 | 357,507 | - | 4.1 | 133,447 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.30 per share. | 02 Jan 2025 | 32,177 | 325,330 | - | 4.3 | 138,361 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.45 per share. | 02 Jan 2025 | 16,576 | 308,754 | - | 4.4 | 73,763 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 4.38 per share. | 27 Dec 2024 | 299 | 321,608 | - | 4.4 | 1,310 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 4.38 per share. | 27 Dec 2024 | 657 | 520,088 | - | 4.4 | 2,878 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.42 per share. | 27 Dec 2024 | 4,566 | 299,226 | - | 4.4 | 20,182 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 4.38 per share. | 27 Dec 2024 | 299 | 303,792 | - | 4.4 | 1,310 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 4.38 per share. | 27 Dec 2024 | 400 | 389,663 | - | 4.4 | 1,752 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 5.00 per share. | 16 Dec 2024 | 100,000 | 574,548 | - | 5 | 500,000 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.06 per share. | 28 Oct 2024 | 1,632 | 321,907 | - | 6.1 | 9,890 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 6.06 per share. | 28 Oct 2024 | 2,688 | 520,745 | - | 6.1 | 16,289 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.06 per share. | 28 Oct 2024 | 1,697 | 311,496 | - | 6.1 | 10,284 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.06 per share. | 28 Oct 2024 | 5,105 | 306,391 | - | 6.1 | 30,936 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 5.95 per share. | 28 Oct 2024 | 2,300 | 304,091 | - | 6.0 | 13,685 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 6.06 per share. | 28 Oct 2024 | 1,621 | 390,063 | - | 6.1 | 9,823 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 7.51 per share. | 27 Sep 2024 | 295 | 323,539 | - | 7.5 | 2,215 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 7.51 per share. | 27 Sep 2024 | 648 | 523,433 | - | 7.5 | 4,866 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.46 per share. | 27 Sep 2024 | 6,162 | 313,193 | - | 7.5 | 45,969 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.51 per share. | 27 Sep 2024 | 295 | 319,355 | - | 7.5 | 2,215 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 7.51 per share. | 27 Sep 2024 | 245 | 391,684 | - | 7.5 | 1,840 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 8.85 per share. | 29 Jul 2024 | 1,638 | 323,834 | - | 8.8 | 14,496 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 8.85 per share. | 29 Jul 2024 | 2,698 | 524,081 | - | 8.8 | 23,877 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 8.51 per share. | 29 Jul 2024 | 9,078 | 319,650 | - | 8.5 | 77,254 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 8.85 per share. | 29 Jul 2024 | 1,702 | 328,728 | - | 8.9 | 15,063 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 8.51 per share. | 29 Jul 2024 | 12,164 | 420,765 | - | 8.5 | 103,516 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 8.19 per share. | 29 Jul 2024 | 13,708 | 391,929 | - | 8.2 | 112,269 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 8.28 per share. | 29 Jul 2024 | 15,128 | 405,637 | - | 8.3 | 125,260 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 8.85 per share. | 29 Jul 2024 | 1,359 | 432,929 | - | 8.8 | 12,027 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 25 Jul 2024 | 50,000 | 816,130 | - | 5.0 | 252,000 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jul 2024 | 36,706 | 482,073 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Jul 2024 | 50,000 | 518,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 9.07 per share. | 25 Jul 2024 | 36,706 | 766,130 | - | 9.1 | 332,923 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 25 Jul 2024 | 36,706 | 802,836 | - | 5.0 | 184,998 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 9.16 per share. | 25 Jul 2024 | 50,000 | 766,130 | - | 9.2 | 458,000 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 5.54 per share. | 30 Jun 2024 | 2,108 | 766,130 | - | 5.5 | 11,678 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.26 per share. | 27 Jun 2024 | 295 | 325,472 | - | 6.3 | 1,847 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 6.26 per share. | 27 Jun 2024 | 648 | 526,779 | - | 6.3 | 4,056 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.26 per share. | 27 Jun 2024 | 295 | 339,508 | - | 6.3 | 1,847 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.24 per share. | 27 Jun 2024 | 9,078 | 330,430 | - | 6.2 | 56,647 | Common Stock |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 5.54 per share. | 27 Jun 2024 | 2,108 | 434,288 | - | 5.5 | 11,678 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 6.26 per share. | 27 Jun 2024 | 245 | 432,180 | - | 6.3 | 1,534 | Common Stock |
| Jami Rubin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 10 Jun 2024 | 42,242 | 0 | - | - | Stock Option (Right to Buy) | |
| Jami Rubin | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 10 Jun 2024 | 42,242 | 67,242 | - | 5.0 | 212,900 | Common Stock |
| Alexis A. Borisy | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Douglas S. Ingram | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Linda A. Hill | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Mark Murcko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Jami Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Sekar Kathiresan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 Jun 2024 | 102,225 | 102,225 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 6.47 per share. | 03 Jun 2024 | 19,864 | 493,470 | - | 6.5 | 128,520 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 7.06 per share. | 03 Jun 2024 | 20,450 | 432,425 | - | 7.1 | 144,377 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 6.64 per share. | 03 Jun 2024 | 40,595 | 452,875 | - | 6.6 | 269,551 | Common Stock |
| Brian R. Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 29 Apr 2024 | 1,623 | 325,767 | - | 6.4 | 10,355 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 29 Apr 2024 | 2,686 | 527,427 | - | 6.4 | 17,137 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 29 Apr 2024 | 1,695 | 339,803 | - | 6.4 | 10,814 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 6.38 per share. | 29 Apr 2024 | 1,345 | 513,334 | - | 6.4 | 8,581 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 7.70 per share. | 27 Mar 2024 | 348 | 327,390 | - | 7.7 | 2,680 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 7.70 per share. | 27 Mar 2024 | 765 | 530,113 | - | 7.7 | 5,891 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 7.70 per share. | 27 Mar 2024 | 348 | 341,498 | - | 7.7 | 2,680 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 7.70 per share. | 27 Mar 2024 | 298 | 514,679 | - | 7.7 | 2,295 | Common Stock |
| Adams Brian | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 9.64 per share. | 29 Jan 2024 | 1,929 | 327,738 | - | 9.6 | 18,596 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 9.64 per share. | 29 Jan 2024 | 2,005 | 341,846 | - | 9.6 | 19,328 | Common Stock |
| A. Donald Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 9.64 per share. | 29 Jan 2024 | 3,178 | 530,878 | - | 9.6 | 30,636 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 9.64 per share. | 29 Jan 2024 | 1,651 | 514,977 | - | 9.6 | 15,916 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 200,000 | 343,851 | - | 0 | Common Stock | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 200,000 | 516,628 | - | 0 | Common Stock | |
| Patel Sanjiv K. | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 762,360 | 764,022 | - | 0 | Common Stock | |
| A. Bergstrom Donald | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 300,000 | 534,056 | - | 0 | Common Stock | |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jan 2024 | 200,000 | 329,667 | - | 0 | Common Stock | |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 11.51 per share. | 27 Dec 2023 | 294 | 143,851 | - | 11.5 | 3,384 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 11.51 per share. | 27 Dec 2023 | 244 | 316,628 | - | 11.5 | 2,808 | Common Stock |
| Bergstrom Donald A. | President, R&D | Sale of securities on an exchange or to another person at price $ 11.51 per share. | 27 Dec 2023 | 977 | 234,056 | - | 11.5 | 11,245 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 11.51 per share. | 27 Dec 2023 | 294 | 129,667 | - | 11.5 | 3,384 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 11.80 per share. | 28 Jul 2023 | 1,628 | 131,887 | - | 11.8 | 19,210 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 11.80 per share. | 28 Jul 2023 | 2,683 | 237,904 | - | 11.8 | 31,659 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 11.80 per share. | 28 Jul 2023 | 1,693 | 146,136 | - | 11.8 | 19,977 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 11.80 per share. | 28 Jul 2023 | 1,352 | 316,808 | - | 11.8 | 15,954 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 12.12 per share. | 27 Jun 2023 | 294 | 133,515 | - | 12.1 | 3,563 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 12.12 per share. | 27 Jun 2023 | 647 | 240,587 | - | 12.1 | 7,842 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 12.12 per share. | 27 Jun 2023 | 294 | 147,829 | - | 12.1 | 3,563 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 12.12 per share. | 27 Jun 2023 | 244 | 318,160 | - | 12.1 | 2,957 | Common Stock |
| Alexis A. Borisy | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Douglas S. Ingram | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Linda A. Hill | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Mark Murcko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Jami Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Sekar Kathiresan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 May 2023 | 66,055 | 66,055 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 May 2023 | 161,818 | 318,404 | - | 0 | Common Stock | |
| Laura Shawver | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 24 May 2023 | 12,099 | 40,000 | - | - | Common Stock | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 11.16 per share. | 28 Apr 2023 | 1,936 | 133,809 | - | 11.2 | 21,606 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 11.16 per share. | 28 Apr 2023 | 2,850 | 241,234 | - | 11.2 | 31,806 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 11.16 per share. | 28 Apr 2023 | 2,012 | 148,123 | - | 11.2 | 22,454 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 11.16 per share. | 28 Apr 2023 | 1,657 | 156,586 | - | 11.2 | 18,492 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 15.36 per share. | 27 Mar 2023 | 347 | 135,745 | - | 15.4 | 5,330 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 15.36 per share. | 27 Mar 2023 | 763 | 244,084 | - | 15.4 | 11,720 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 15.36 per share. | 27 Mar 2023 | 347 | 150,135 | - | 15.4 | 5,330 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 15.36 per share. | 27 Mar 2023 | 297 | 158,243 | - | 15.4 | 4,562 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.98 per share. | 07 Feb 2023 | 14,000 | 0 | - | 21.0 | 293,720 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 07 Feb 2023 | 14,000 | 14,000 | - | 5.0 | 70,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.45 per share. | 07 Feb 2023 | 14,000 | 0 | - | 21.5 | 300,300 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 07 Feb 2023 | 14,000 | 14,000 | - | 5.0 | 70,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 07 Feb 2023 | 14,000 | 14,000 | - | 5.0 | 70,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.55 per share. | 07 Feb 2023 | 14,000 | 0 | - | 20.6 | 287,700 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2023 | 14,000 | 596,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2023 | 14,000 | 582,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Feb 2023 | 14,000 | 568,779 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 21.56 per share. | 30 Jan 2023 | 864 | 136,092 | - | 21.6 | 18,628 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 21.56 per share. | 30 Jan 2023 | 1,429 | 244,847 | - | 21.6 | 30,809 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.56 per share. | 30 Jan 2023 | 864 | 150,482 | - | 21.6 | 18,628 | Common Stock |
| Peter Rahmer | See remarks | Sale of securities on an exchange or to another person at price $ 21.56 per share. | 30 Jan 2023 | 740 | 158,540 | - | 21.6 | 15,954 | Common Stock |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 97,630 | 97,630 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 85,425 | 136,956 | - | 0 | Common Stock | |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 73,220 | 73,220 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 160,390 | 160,390 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 160,390 | 246,276 | - | 0 | Common Stock | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 160,390 | 160,390 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2023 | 28,000 | 610,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2023 | 28,000 | 638,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jan 2023 | 28,000 | 666,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.02 per share. | 17 Jan 2023 | 28,000 | 254,554 | - | 20.0 | 560,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 17 Jan 2023 | 28,000 | 282,554 | - | 5.0 | 141,120 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.87 per share. | 17 Jan 2023 | 28,000 | 254,554 | - | 20.9 | 584,360 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 17 Jan 2023 | 28,000 | 282,554 | - | 5.0 | 141,120 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.23 per share. | 17 Jan 2023 | 28,000 | 254,554 | - | 20.2 | 566,440 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 701,680 | 701,680 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 17 Jan 2023 | 28,000 | 282,554 | - | 5.0 | 141,120 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 701,680 | 701,680 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 97,630 | 97,630 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 101,115 | 151,346 | - | 0 | Common Stock | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 104,600 | 104,600 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 97,630 | 97,630 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 97,630 | 97,630 | - | - | Stock Option (Right to Buy) | |
| Peter Rahmer | See remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jan 2023 | 97,630 | 159,280 | - | 0 | Common Stock | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 12 Jan 2023 | 9,994 | 51,531 | - | 20 | 199,880 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 254,554 | 687,355 | - | 0 | Common Stock | |
| Sanjiv K. Patel | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 254,554 | 0 | - | 0 | Common Stock | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 14.49 per share. | 27 Dec 2022 | 295 | 61,525 | - | 14.5 | 4,275 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 14.49 per share. | 27 Dec 2022 | 980 | 85,886 | - | 14.5 | 14,200 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 14.49 per share. | 27 Dec 2022 | 445 | 50,231 | - | 14.5 | 6,448 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 08 Nov 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Nov 2022 | 9,825 | 694,779 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Nov 2022 | 18,175 | 0 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Nov 2022 | 14,000 | 18,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 08 Nov 2022 | 9,825 | 254,554 | - | 20 | 196,500 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 08 Nov 2022 | 9,825 | 264,379 | - | 5.0 | 49,518 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 08 Nov 2022 | 18,175 | 254,554 | - | 20 | 363,500 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 08 Nov 2022 | 18,175 | 272,729 | - | 4.1 | 74,881 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.18 per share. | 08 Nov 2022 | 14,000 | 254,554 | - | 20.2 | 282,520 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 21.54 per share. | 28 Oct 2022 | 728 | 61,820 | - | 21.5 | 15,681 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 28 Oct 2022 | 8,000 | 94,866 | - | 4.1 | 32,960 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 22.75 per share. | 28 Oct 2022 | 8,000 | 86,866 | - | 22.8 | 182,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 21.54 per share. | 28 Oct 2022 | 1,817 | 86,866 | - | 21.5 | 39,138 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Oct 2022 | 8,000 | 93,456 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.54 per share. | 28 Oct 2022 | 1,099 | 50,676 | - | 21.5 | 23,672 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 21.54 per share. | 28 Oct 2022 | 448 | 45,164 | - | 21.5 | 9,650 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.18 per share. | 11 Oct 2022 | 14,000 | 254,554 | - | 21.2 | 296,520 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 14,000 | 32,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 14,000 | 46,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 11 Oct 2022 | 14,000 | 60,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 20.58 per share. | 11 Oct 2022 | 14,000 | 254,554 | - | 20.6 | 288,120 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 11 Oct 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 11 Oct 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 21.36 per share. | 11 Oct 2022 | 14,000 | 254,554 | - | 21.4 | 299,040 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 11 Oct 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 22.43 per share. | 03 Oct 2022 | 8,000 | 88,683 | - | 22.4 | 179,440 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 03 Oct 2022 | 8,000 | 96,683 | - | 4.1 | 32,960 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Oct 2022 | 8,000 | 101,456 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 22.73 per share. | 27 Sep 2022 | 294 | 62,548 | - | 22.7 | 6,683 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 22.73 per share. | 27 Sep 2022 | 976 | 88,683 | - | 22.7 | 22,184 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 22.73 per share. | 27 Sep 2022 | 443 | 51,775 | - | 22.7 | 10,069 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 22.73 per share. | 27 Sep 2022 | 259 | 45,612 | - | 22.7 | 5,887 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 13 Sep 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.47 per share. | 13 Sep 2022 | 14,000 | 254,554 | - | 23.5 | 328,580 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2022 | 14,000 | 74,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2022 | 14,000 | 88,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2022 | 14,000 | 102,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 23.80 per share. | 13 Sep 2022 | 14,000 | 254,554 | - | 23.8 | 333,200 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 13 Sep 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 25.45 per share. | 13 Sep 2022 | 14,000 | 254,554 | - | 25.5 | 356,300 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 13 Sep 2022 | 14,000 | 268,554 | - | 4.1 | 57,680 | Common Stock |
| Mark Murcko | Director | Sale of securities on an exchange or to another person at price $ 29.95 per share. | 08 Sep 2022 | 25,000 | 996,952 | - | 30.0 | 748,750 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Sep 2022 | 25,000 | 109,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 08 Sep 2022 | 25,000 | 89,659 | - | 30 | 750,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 08 Sep 2022 | 25,000 | 114,659 | - | 4.1 | 103,000 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 08 Sep 2022 | 26,257 | 52,218 | - | 30 | 787,710 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 08 Sep 2022 | 26,257 | 0 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 08 Sep 2022 | 26,257 | 78,475 | - | 4.1 | 108,179 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 02 Sep 2022 | 4,900 | 94,559 | - | 4.1 | 20,188 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Sep 2022 | 4,900 | 134,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 25.46 per share. | 02 Sep 2022 | 4,900 | 89,659 | - | 25.5 | 124,754 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Sep 2022 | 8,100 | 139,356 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 01 Sep 2022 | 8,100 | 97,759 | - | 4.1 | 33,372 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 23.07 per share. | 01 Sep 2022 | 8,100 | 89,659 | - | 23.1 | 186,867 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Aug 2022 | 15,000 | 147,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 24 Aug 2022 | 15,000 | 104,659 | - | 4.1 | 61,800 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 25.00 per share. | 24 Aug 2022 | 15,000 | 89,659 | - | 25 | 375,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 05 Aug 2022 | 8,000 | 97,659 | - | 4.1 | 32,960 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 05 Aug 2022 | 8,000 | 89,659 | - | 20 | 160,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 05 Aug 2022 | 8,000 | 162,456 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 21.27 per share. | 28 Jul 2022 | 734 | 62,842 | - | 21.3 | 15,612 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 21.27 per share. | 28 Jul 2022 | 1,835 | 89,659 | - | 21.3 | 39,030 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 21.26 per share. | 28 Jul 2022 | 734 | 52,218 | - | 21.3 | 15,605 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 21.27 per share. | 28 Jul 2022 | 452 | 45,871 | - | 21.3 | 9,614 | Common Stock |
| Sekar Kathiresan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jul 2022 | 71,881 | 71,881 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 06 Jul 2022 | 8,000 | 91,494 | - | 20 | 160,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 Jul 2022 | 8,000 | 170,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 06 Jul 2022 | 8,000 | 99,494 | - | 4.1 | 32,960 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 14.24 per share. | 30 Jun 2022 | 814 | 254,554 | - | 14.2 | 11,591 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 20.31 per share. | 27 Jun 2022 | 300 | 63,576 | - | 20.3 | 6,093 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 20.31 per share. | 27 Jun 2022 | 300 | 52,952 | - | 20.3 | 6,093 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 20.31 per share. | 27 Jun 2022 | 265 | 46,323 | - | 20.3 | 5,382 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.00 per share. | 24 Jun 2022 | 8,000 | 92,493 | - | 20 | 160,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Jun 2022 | 8,000 | 178,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.31 per share. | 24 Jun 2022 | 999 | 91,494 | - | 20.3 | 20,290 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 24 Jun 2022 | 8,000 | 100,493 | - | 4.1 | 32,960 | Common Stock |
| Alexis A. Borisy | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Douglas S. Ingram | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Linda A. Hill | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Mark Murcko | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Laura Shawver | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Jami Rubin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2022 | 41,597 | 41,597 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 25.57 per share. | 28 Apr 2022 | 708 | 63,876 | - | 25.6 | 18,104 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Apr 2022 | 13,000 | 186,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 24.62 per share. | 28 Apr 2022 | 13,000 | 92,493 | - | 24.6 | 320,060 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 28 Apr 2022 | 13,000 | 105,493 | - | 4.1 | 53,560 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 25.57 per share. | 28 Apr 2022 | 1,811 | 92,493 | - | 25.6 | 46,307 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 25.57 per share. | 28 Apr 2022 | 725 | 53,252 | - | 25.6 | 18,538 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 25.57 per share. | 28 Apr 2022 | 435 | 46,588 | - | 25.6 | 11,123 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 12 Apr 2022 | 14,000 | 267,740 | - | 5.0 | 70,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Apr 2022 | 14,000 | 704,604 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Apr 2022 | 14,000 | 116,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Apr 2022 | 14,000 | 718,604 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Apr 2022 | 14,000 | 130,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Apr 2022 | 28,000 | 144,175 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.51 per share. | 12 Apr 2022 | 14,000 | 253,740 | - | 30.5 | 427,140 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 30.51 per share. | 12 Apr 2022 | 14,000 | 253,740 | - | 30.5 | 427,140 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 12 Apr 2022 | 14,000 | 267,740 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 31.94 per share. | 12 Apr 2022 | 14,000 | 253,740 | - | 31.9 | 447,160 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 5.04 per share. | 12 Apr 2022 | 14,000 | 267,740 | - | 5.0 | 70,560 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 31.96 per share. | 12 Apr 2022 | 14,000 | 253,740 | - | 32.0 | 447,440 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 12 Apr 2022 | 14,000 | 267,740 | - | 4.1 | 57,680 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Sale of securities on an exchange or to another person at price $ 31.80 per share. | 12 Apr 2022 | 28,000 | 253,740 | - | 31.8 | 890,400 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 12 Apr 2022 | 28,000 | 281,740 | - | 4.1 | 115,360 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 01 Apr 2022 | 18,000 | 112,304 | - | 4.1 | 74,160 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Apr 2022 | 18,000 | 199,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 30.32 per share. | 01 Apr 2022 | 18,000 | 94,304 | - | 30.3 | 545,760 | Common Stock |
| Brian Adams | Chief Legal Officer | Sale of securities on an exchange or to another person at price $ 29.87 per share. | 29 Mar 2022 | 333 | 64,584 | - | 29.9 | 9,947 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 29.87 per share. | 29 Mar 2022 | 622 | 94,304 | - | 29.9 | 18,579 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 29.87 per share. | 29 Mar 2022 | 282 | 53,977 | - | 29.9 | 8,423 | Common Stock |
| Andy Porter | Chief Administrative Officer | Sale of securities on an exchange or to another person at price $ 29.87 per share. | 29 Mar 2022 | 294 | 47,023 | - | 29.9 | 8,782 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 24 Mar 2022 | 10,000 | 94,926 | - | 30 | 300,000 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Mar 2022 | 10,000 | 217,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 24 Mar 2022 | 10,000 | 104,926 | - | 4.1 | 41,200 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 24 Mar 2022 | 13,286 | 67,545 | - | 4.1 | 54,738 | Common Stock |
| Thomas Catinazzo | Chief Financial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Mar 2022 | 13,286 | 26,257 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Sale of securities on an exchange or to another person at price $ 30.00 per share. | 24 Mar 2022 | 13,286 | 54,259 | - | 30 | 398,580 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 23.88 per share. | 01 Mar 2022 | 8,000 | 94,926 | - | 23.9 | 191,040 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2022 | 8,000 | 237,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 01 Mar 2022 | 8,000 | 102,926 | - | 4.1 | 32,960 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.94 per share. | 22 Feb 2022 | 8,000 | 109,920 | - | 20.9 | 167,520 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 22 Feb 2022 | 8,000 | 245,456 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.97 per share. | 22 Feb 2022 | 2,752 | 94,926 | - | 21.0 | 57,709 | Common Stock |
| Donald A. Bergstrom | President, R&D | Sale of securities on an exchange or to another person at price $ 20.94 per share. | 22 Feb 2022 | 12,242 | 97,678 | - | 20.9 | 256,347 | Common Stock |
| Donald A. Bergstrom | President, R&D | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 22 Feb 2022 | 8,000 | 117,920 | - | 4.1 | 32,960 | Common Stock |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 78,540 | 78,540 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | Chief Legal Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 39,270 | 64,917 | - | 0 | Common Stock | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 129,900 | 129,900 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | President, R&D | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 64,950 | 109,920 | - | 0 | Common Stock | |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 527,140 | 527,140 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 39,270 | 54,259 | - | 0 | Common Stock | |
| Thomas Catinazzo | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 78,540 | 78,540 | - | - | Stock Option (Right to Buy) | |
| Andy Porter | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 48,340 | 48,340 | - | - | Stock Option (Right to Buy) | |
| Andy Porter | Chief Administrative Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Jan 2022 | 24,170 | 47,317 | - | 0 | Common Stock | |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 33.10 per share. | 27 Dec 2021 | 295 | 24,989 | - | 33.1 | 9,765 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 33.10 per share. | 27 Dec 2021 | 649 | 44,970 | - | 33.1 | 21,482 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 33.10 per share. | 27 Dec 2021 | 295 | 14,989 | - | 33.1 | 9,765 | Common Stock |
| Andy Porter | See Remarks | Sale of securities on an exchange or to another person at price $ 33.10 per share. | 27 Dec 2021 | 260 | 23,147 | - | 33.1 | 8,606 | Common Stock |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 35.42 per share. | 15 Nov 2021 | 6,500 | 25,284 | - | 35.4 | 230,230 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2021 | 6,500 | 140,786 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 15 Nov 2021 | 6,500 | 31,784 | - | 4.1 | 26,780 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 15 Nov 2021 | 22,500 | 37,784 | - | 4.1 | 92,700 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 15 Nov 2021 | 22,500 | 39,543 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 35.40 per share. | 15 Nov 2021 | 22,500 | 15,284 | - | 35.4 | 796,500 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 34.15 per share. | 15 Oct 2021 | 30,000 | 45,619 | - | 34.2 | 1,024,500 | Common Stock |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 36.87 per share. | 27 Sep 2021 | 293 | 25,284 | - | 36.9 | 10,803 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 36.87 per share. | 27 Sep 2021 | 646 | 75,619 | - | 36.9 | 23,818 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 36.87 per share. | 27 Sep 2021 | 293 | 15,284 | - | 36.9 | 10,803 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 13 Sep 2021 | 6,500 | 32,077 | - | 4.1 | 26,780 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2021 | 6,500 | 147,286 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 35.02 per share. | 13 Sep 2021 | 6,500 | 25,577 | - | 35.0 | 227,630 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 13 Sep 2021 | 22,500 | 38,077 | - | 4.1 | 92,700 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Sep 2021 | 22,500 | 62,043 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 13 Sep 2021 | 22,500 | 15,577 | - | 35 | 787,500 | Common Stock |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 35.81 per share. | 28 Jun 2021 | 293 | 25,577 | - | 35.8 | 10,492 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 35.81 per share. | 28 Jun 2021 | 976 | 76,265 | - | 35.8 | 34,951 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 35.81 per share. | 28 Jun 2021 | 293 | 15,577 | - | 35.8 | 10,492 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 33.75 per share. | 16 Jun 2021 | 42,242 | 77,241 | - | 33.8 | 1,425,668 | Common Stock |
| Donald A. Bergstrom | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 16 Jun 2021 | 42,242 | 119,483 | - | 4.1 | 174,037 | Common Stock |
| Donald A. Bergstrom | See Remarks | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Jun 2021 | 42,242 | 253,456 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 07 Jun 2021 | 6,500 | 32,370 | - | 4.1 | 26,780 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jun 2021 | 6,500 | 153,786 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 07 Jun 2021 | 6,500 | 25,870 | - | 35 | 227,500 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 07 Jun 2021 | 22,500 | 38,370 | - | 4.1 | 92,700 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 07 Jun 2021 | 22,500 | 84,543 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 07 Jun 2021 | 22,500 | 15,870 | - | 35 | 787,500 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Apr 2021 | 6,500 | 160,286 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 26 Apr 2021 | 6,500 | 32,370 | - | 4.1 | 26,780 | Common Stock |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 26 Apr 2021 | 6,500 | 25,870 | - | 35 | 227,500 | Common Stock |
| Donald A. Bergstrom | See Remarks | Sale of securities on an exchange or to another person at price $ 32.36 per share. | 16 Apr 2021 | 56,324 | 77,241 | - | 32.4 | 1,822,645 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 30 Mar 2021 | 22,500 | 38,370 | - | 4.1 | 92,700 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Sale of securities on an exchange or to another person at price $ 35.00 per share. | 30 Mar 2021 | 22,500 | 15,870 | - | 35 | 787,500 | Common Stock |
| Thomas Catinazzo | Senior Vice President, Finance | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 30 Mar 2021 | 22,500 | 107,043 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 15,870 | 25,870 | - | 0 | Common Stock | |
| Brian Adams | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 31,740 | 31,740 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 34,999 | 133,565 | - | 0 | Common Stock | |
| Donald A. Bergstrom | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 69,998 | 69,998 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 26 Mar 2021 | 150,000 | 674,548 | - | 0 | Common Stock | |
| Sanjiv K. Patel | Director, President and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 26 Mar 2021 | 150,000 | 253,082 | - | 0 | Common Stock | |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 325,000 | 325,000 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 31,740 | 31,740 | - | - | Stock Option (Right to Buy) | |
| Thomas Catinazzo | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Mar 2021 | 15,870 | 15,870 | - | 0 | Common Stock | |
| Alexis A. Borisy | Director | Other type of transaction at price $ 0.00 per share. | 11 Mar 2021 | 28,538 | 234,175 | - | 0 | Common Stock | |
| Alexis A. Borisy | Director | Other type of transaction at price $ 0.00 per share. | 19 Feb 2021 | 30,194 | 205,637 | - | 0 | Common Stock | |
| Alexis A. Borisy | Director | Other type of transaction at price $ 0.00 per share. | 05 Feb 2021 | 70,956 | 175,443 | - | 0 | Common Stock | |
| Brian Adams | General Counsel | Sale of securities on an exchange or to another person at price $ 55.05 per share. | 28 Jan 2021 | 5,000 | 10,000 | - | 55.1 | 275,250 | Common Stock |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Jan 2021 | 5,000 | 166,786 | - | - | Stock Option (Right to Buy) | |
| Brian Adams | General Counsel | Exercise or conversion of derivative security received from the company (such as an option) at price $ 4.12 per share. | 28 Jan 2021 | 5,000 | 15,000 | - | 4.1 | 20,600 | Common Stock |
| Brian Adams | General Counsel | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Dec 2020 | 67,588 | 67,588 | - | - | Stock Option (Right to Buy) | |
| Donald A. Bergstrom | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Dec 2020 | 126,727 | 126,727 | - | - | Stock Option (Right to Buy) | |
| Sanjiv K. Patel | Director, President and CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Dec 2020 | 753,804 | 753,804 | - | - | Stock Option (Right to Buy) | |
| Tom Catinazzo | Senior Vice President, Finance | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Dec 2020 | 63,363 | 63,363 | - | - | Stock Option (Right to Buy) | |
| Alexis A. Borisy | Director | 20 Jul 2020 | 104,487 | 104,487 | - | 0 | Common Stock | ||
| Alexis A. Borisy | Director | 20 Jul 2020 | 371,027 | 0 | - | - | Series C Convertible Preferred Stock | ||
| Douglas S. Ingram | Director | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 20 Jul 2020 | 25,000 | 25,000 | - | 20 | 500,000 | Common Stock |
| Mark Murcko | Director | 20 Jul 2020 | 278,829 | 996,952 | - | - | Common Stock | ||
| Mark Murcko | Director | 20 Jul 2020 | 281,617 | 718,123 | - | - | Common Stock | ||
| Mark Murcko | Director | 20 Jul 2020 | 990,099 | 0 | - | - | Series B Convertible Preferred Stock | ||
| Mark Murcko | Director | 20 Jul 2020 | 1,000,000 | 0 | - | - | Series A Convertible Preferred Stock | ||
| Mark Murcko | Director | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 20 Jul 2020 | 25,000 | 1,021,952 | - | 20 | 500,000 | Common Stock |
| Brian Adams | General Counsel | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 20 Jul 2020 | 10,000 | 10,000 | - | 20 | 200,000 | Common Stock |
| Sanjiv K. Patel | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 20 Jul 2020 | 25,000 | 403,082 | - | 20 | 500,000 | Common Stock |
| Jami Rubin | Director | Purchase of securities on an exchange or from another person at price $ 20.00 per share. | 20 Jul 2020 | 25,000 | 25,000 | - | 20 | 500,000 | Common Stock |